The Radiology Partners (RP) Neuroradiology National Subspecialty Division (NSD) presents our newest Rad to Rad Learning case.
Peer Learning Opportunity
Early imaging-based diagnosis is critical, as hemorrhagic complications can be mitigated by avoiding certain therapies.
Superficial siderosis, sequalae of bilateral microhemorrhages and large parenchymal hemorrhage.


Practical Insights 
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- Causes up to 1/5 of primary intracranial hemorrhage in patients >60 years.
- Boston criteria are used for diagnosis without biopsy using presence of multiple asymmetric lobar microhemorrhages, cortical superficial siderosis, and lobar ICH.
- Other markers are multiple dilated perivascular spaces and white matter T2 hyperintensities (70%).
- May show sulcal or leptomeningeal enhancement or focal nonhemorrhagic mass (amyloidoma) extending to the ventricular wall in younger patients.
Takeaway: Suspect CAA in normotensive patients with multiple types of non-traumatic hemorrhages.
Shared to improve patient safety and healthcare delivery in the provision of radiology services. The circumstances and facts are changed, altered, or deidentified to preserve confidentiality. Privileges have not been waived.
The Neuroradiology National Subspecialty Division (NSD) is part of RP’s Clinical Value Team, which works to elevate patient care and enhance value through innovation, collaboration and education. To advance this goal, our radiologists and advanced practice providers are committed to sharing peer learning as valuable reminders and insights about what we encounter in our day-to-day practice. Check back here and on X, LinkedIn and Instagram to see these common cases and our findings.
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