Rad to Rad Learning: Solid Pulmonary Nodules on FDG PET/CT

The Radiology Partners (RP) NMMI Radiology National Subspecialty Division (NSD) presents our newest Rad to Rad Learning case.

Peer Learning Opportunity

Low-level FDG uptake in a solid pulmonary nodule does not exclude malignancy.

Shared to improve patient safety and healthcare delivery in the provision of radiology services. The circumstances and facts are changed, altered, or deidentified to preserve confidentiality. Privileges have not been waived.

Practical Insights

• • Historically, SUV > 2.5 has been shown to have higher positive predictive value for malignancy.

  • However, SUV <2.5 is not definitively benign.

  • Nodule morphology and change over time are as important as SUV.

  • If low FDG activity, recommend follow-up CT as a minimum

No SUV threshold reliably differentiates malignant from benign solid nodules.

The NMMI Radiology National Subspecialty Division (NSD) is part of RP’s Clinical Value Team, which works to elevate patient care and enhance value through innovation, collaboration and education. To advance this goal, our radiologists and advanced practice providers are committed to sharing peer learning as valuable reminders and insights about what we encounter in our day-to-day practice. Check back here and on X, LinkedIn and Instagram to see these common cases and our findings.

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